Week RS1 • 2025-09-07 • vs CAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rico Dowdle |
RB |
3 |
12 |
4.0 |
0 |
9 |
| 2 |
Chuba Hubbard |
RB |
16 |
57 |
3.6 |
0 |
9 |
Week RS2 • 2025-09-14 • vs CIN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chase Brown |
RB |
16 |
47 |
2.9 |
0 |
11 |
Week RS3 • 2025-09-21 • vs HOU (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
6 |
27 |
4.5 |
0 |
8 |
| 2 |
Nick Chubb |
RB |
9 |
38 |
4.2 |
0 |
8 |
Week RS4 • 2025-09-28 • vs SF (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Christian McCaffrey |
RB |
17 |
49 |
2.9 |
0 |
11 |
| 2 |
Brian Robinson Jr. |
RB |
5 |
21 |
4.2 |
0 |
7 |
Week RS5 • 2025-10-06 • vs KC (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Isiah Pacheco |
RB |
7 |
36 |
5.1 |
0 |
16 |
| 2 |
Kareem Hunt |
RB |
7 |
49 |
7.0 |
2 |
33 |
Week RS6 • 2025-10-12 • vs SEA (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
10 |
34 |
3.4 |
0 |
10 |
| 2 |
Zach Charbonnet |
RB |
12 |
24 |
2.0 |
0 |
8 |
Week RS7 • 2025-10-19 • vs LAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
12 |
54 |
4.5 |
0 |
10 |
| 2 |
Blake Corum |
RB |
12 |
37 |
3.1 |
0 |
6 |
Week RS10 • 2025-11-09 • vs HOU (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
14 |
63 |
4.5 |
1 |
21 |
| 2 |
Nick Chubb |
RB |
5 |
47 |
9.4 |
0 |
19 |
Week RS11 • 2025-11-16 • vs LAC (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kimani Vidal |
RB |
5 |
13 |
2.6 |
0 |
4 |
Week RS12 • 2025-11-23 • vs ARI (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Michael Carter |
RB |
5 |
28 |
5.6 |
0 |
11 |
Week RS13 • 2025-11-30 • vs TEN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tony Pollard |
RB |
10 |
60 |
6.0 |
0 |
15 |
| 2 |
Tyjae Spears |
RB |
2 |
-1 |
-0.5 |
0 |
2 |
Week RS14 • 2025-12-07 • vs IND (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jonathan Taylor |
RB |
21 |
74 |
3.5 |
1 |
14 |
| 2 |
Ameer Abdullah |
RB |
1 |
4 |
4.0 |
0 |
4 |
Week RS15 • 2025-12-14 • vs NYJ (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Breece Hall |
RB |
12 |
23 |
1.9 |
0 |
13 |
| 2 |
Isaiah Davis |
RB |
9 |
58 |
6.4 |
1 |
24 |
