Week RS1 • 2025-09-07 • vs LV (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Ashton Jeanty |
RB |
19 |
38 |
2.0 |
1 |
9 |
| 2 |
Zamir White |
RB |
3 |
8 |
2.7 |
0 |
5 |
Week RS2 • 2025-09-14 • vs MIA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
De'Von Achane |
RB |
11 |
30 |
2.7 |
0 |
9 |
| 2 |
Ollie Gordon II |
RB |
1 |
8 |
8.0 |
0 |
8 |
Week RS3 • 2025-09-21 • vs PIT (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jaylen Warren |
RB |
18 |
47 |
2.6 |
0 |
11 |
| 2 |
Kenneth Gainwell |
RB |
4 |
16 |
4.0 |
1 |
13 |
Week RS4 • 2025-09-28 • vs CAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rico Dowdle |
RB |
9 |
32 |
3.6 |
0 |
10 |
| 2 |
Chuba Hubbard |
RB |
10 |
49 |
4.9 |
0 |
11 |
Week RS5 • 2025-10-05 • vs BUF (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
James Cook |
RB |
15 |
49 |
3.3 |
0 |
9 |
| 2 |
Ray Davis |
RB |
2 |
1 |
0.5 |
0 |
1 |
Week RS6 • 2025-10-12 • vs NO (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Alvin Kamara |
RB |
10 |
31 |
3.1 |
0 |
7 |
Week RS7 • 2025-10-19 • vs TEN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tony Pollard |
RB |
6 |
18 |
3.0 |
0 |
6 |
| 2 |
Tyjae Spears |
RB |
5 |
22 |
4.4 |
0 |
8 |
Week RS8 • 2025-10-26 • vs CLE (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Quinshon Judkins |
RB |
9 |
19 |
2.1 |
0 |
6 |
| 2 |
Dylan Sampson |
RB |
3 |
0 |
0.0 |
0 |
1 |
Week RS10 • 2025-11-09 • vs TB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rachaad White |
RB |
10 |
38 |
3.8 |
0 |
7 |
| 2 |
Sean Tucker |
RB |
9 |
53 |
5.9 |
0 |
18 |
Week RS11 • 2025-11-13 • vs NYJ (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Breece Hall |
RB |
14 |
58 |
4.1 |
0 |
11 |
| 2 |
Isaiah Davis |
RB |
2 |
11 |
5.5 |
0 |
7 |
Week RS12 • 2025-11-23 • vs CIN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chase Brown |
RB |
19 |
107 |
5.6 |
0 |
21 |
| 2 |
Tahj Brooks |
RB |
2 |
5 |
2.5 |
0 |
3 |
Week RS13 • 2025-12-01 • vs NYG (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tyrone Tracy Jr. |
RB |
10 |
36 |
3.6 |
0 |
9 |
| 2 |
Devin Singletary |
RB |
12 |
68 |
5.7 |
1 |
22 |
Week RS15 • 2025-12-14 • vs BUF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
James Cook III |
RB |
22 |
107 |
4.9 |
2 |
12 |
| 2 |
Ty Johnson |
RB |
4 |
13 |
3.3 |
0 |
9 |
