Week RS1 • 2025-09-07 • vs NO (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Alvin Kamara |
RB |
11 |
45 |
4.1 |
1 |
18 |
| 2 |
Devin Neal |
RB |
2 |
9 |
4.5 |
0 |
5 |
Week RS2 • 2025-09-14 • vs CAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rico Dowdle |
RB |
6 |
9 |
1.5 |
0 |
5 |
| 2 |
Chuba Hubbard |
RB |
10 |
38 |
3.8 |
0 |
14 |
Week RS3 • 2025-09-21 • vs SF (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Christian McCaffrey |
RB |
17 |
52 |
3.1 |
0 |
15 |
| 2 |
Brian Robinson Jr. |
RB |
2 |
22 |
11.0 |
0 |
19 |
Week RS4 • 2025-09-25 • vs SEA (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
19 |
81 |
4.3 |
0 |
21 |
| 2 |
Zach Charbonnet |
RB |
12 |
39 |
3.3 |
1 |
15 |
Week RS5 • 2025-10-05 • vs TEN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tony Pollard |
RB |
14 |
67 |
4.8 |
1 |
14 |
| 2 |
Tyjae Spears |
RB |
4 |
14 |
3.5 |
0 |
5 |
Week RS6 • 2025-10-12 • vs IND (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jonathan Taylor |
RB |
21 |
123 |
5.9 |
1 |
30 |
| 2 |
Ameer Abdullah |
RB |
1 |
7 |
7.0 |
0 |
7 |
Week RS7 • 2025-10-19 • vs GB (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Josh Jacobs |
RB |
13 |
55 |
4.2 |
2 |
10 |
| 2 |
Emanuel Wilson |
RB |
6 |
17 |
2.8 |
0 |
8 |
Week RS9 • 2025-11-03 • vs DAL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Javonte Williams |
RB |
15 |
83 |
5.5 |
0 |
19 |
| 2 |
Malik Davis |
RB |
1 |
3 |
3.0 |
0 |
3 |
Week RS10 • 2025-11-09 • vs SEA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
14 |
67 |
4.8 |
0 |
24 |
| 2 |
Zach Charbonnet |
RB |
14 |
83 |
5.9 |
1 |
30 |
Week RS11 • 2025-11-16 • vs SF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Christian McCaffrey |
RB |
13 |
81 |
6.2 |
2 |
20 |
| 2 |
Brian Robinson Jr. |
RB |
8 |
24 |
3.0 |
0 |
7 |
Week RS12 • 2025-11-23 • vs JAX (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
15 |
86 |
5.7 |
0 |
45 |
| 2 |
Bhayshul Tuten |
RB |
7 |
17 |
2.4 |
0 |
4 |
Week RS13 • 2025-11-30 • vs TB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bucky Irving |
RB |
17 |
61 |
3.6 |
1 |
13 |
| 2 |
Rachaad White |
RB |
2 |
7 |
3.5 |
0 |
5 |
Week RS14 • 2025-12-07 • vs LAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
13 |
84 |
6.5 |
1 |
18 |
| 2 |
Blake Corum |
RB |
12 |
128 |
10.7 |
2 |
48 |
Week RS15 • 2025-12-14 • vs HOU (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
7 |
30 |
4.3 |
0 |
11 |
| 2 |
Jawhar Jordan |
RB |
15 |
101 |
6.7 |
0 |
50 |
