Week RS1 • 2025-09-07 • vs LAR (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
18 |
66 |
3.7 |
1 |
9 |
| 2 |
Blake Corum |
RB |
1 |
2 |
2.0 |
0 |
2 |
Week RS2 • 2025-09-15 • vs TB (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bucky Irving |
RB |
17 |
71 |
4.2 |
0 |
10 |
| 2 |
Rachaad White |
RB |
10 |
65 |
6.5 |
1 |
16 |
Week RS3 • 2025-09-21 • vs JAX (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
16 |
56 |
3.5 |
1 |
10 |
| 2 |
Bhayshul Tuten |
RB |
6 |
21 |
3.5 |
1 |
6 |
Week RS4 • 2025-09-28 • vs TEN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tony Pollard |
RB |
14 |
64 |
4.6 |
0 |
21 |
| 2 |
Julius Chestnut |
RB |
1 |
0 |
0.0 |
0 |
0 |
Week RS5 • 2025-10-05 • vs BAL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Derrick Henry |
RB |
15 |
33 |
2.2 |
1 |
7 |
| 2 |
Keaton Mitchell |
RB |
3 |
8 |
2.7 |
0 |
6 |
Week RS7 • 2025-10-20 • vs SEA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
17 |
66 |
3.9 |
0 |
16 |
| 2 |
Zach Charbonnet |
RB |
12 |
49 |
4.1 |
2 |
15 |
Week RS8 • 2025-10-26 • vs SF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Christian McCaffrey |
RB |
8 |
25 |
3.1 |
0 |
9 |
Week RS10 • 2025-11-09 • vs JAX (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
16 |
58 |
3.6 |
1 |
13 |
| 2 |
Bhayshul Tuten |
RB |
4 |
5 |
1.3 |
0 |
6 |
Week RS11 • 2025-11-16 • vs TEN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tony Pollard |
RB |
10 |
22 |
2.2 |
0 |
7 |
| 2 |
Tyjae Spears |
RB |
4 |
3 |
0.8 |
0 |
1 |
Week RS12 • 2025-11-20 • vs BUF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
James Cook III |
RB |
17 |
116 |
6.8 |
1 |
45 |
| 2 |
Ty Johnson |
RB |
2 |
7 |
3.5 |
0 |
9 |
Week RS13 • 2025-11-30 • vs IND (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jonathan Taylor |
RB |
21 |
85 |
4.0 |
0 |
12 |
Week RS14 • 2025-12-07 • vs KC (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Isiah Pacheco |
RB |
9 |
30 |
3.3 |
0 |
6 |
| 2 |
Kareem Hunt |
RB |
12 |
30 |
2.5 |
1 |
6 |
Week RS15 • 2025-12-14 • vs ARI (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Michael Carter |
RB |
14 |
56 |
4.0 |
0 |
8 |
| 2 |
Emari Demercado |
RB |
1 |
1 |
1.0 |
0 |
1 |
