Week RS1 • 2025-09-04 • vs DAL (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Javonte Williams |
RB |
15 |
54 |
3.6 |
2 |
11 |
Week RS2 • 2025-09-14 • vs KC (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Isiah Pacheco |
RB |
10 |
22 |
2.2 |
0 |
7 |
| 2 |
Kareem Hunt |
RB |
8 |
31 |
3.9 |
0 |
11 |
Week RS3 • 2025-09-21 • vs LAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
20 |
94 |
4.7 |
0 |
13 |
| 2 |
Blake Corum |
RB |
8 |
53 |
6.6 |
0 |
12 |
Week RS4 • 2025-09-28 • vs TB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bucky Irving |
RB |
15 |
63 |
4.2 |
0 |
15 |
| 2 |
Rachaad White |
RB |
6 |
17 |
2.8 |
0 |
5 |
Week RS5 • 2025-10-05 • vs DEN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
RJ Harvey |
RB |
4 |
12 |
3.0 |
0 |
8 |
Week RS6 • 2025-10-09 • vs NYG (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tyrone Tracy Jr. |
RB |
4 |
6 |
1.5 |
0 |
3 |
| 2 |
Devin Singletary |
RB |
3 |
10 |
3.3 |
0 |
6 |
Week RS7 • 2025-10-19 • vs MIN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jordan Mason |
RB |
15 |
57 |
3.8 |
1 |
12 |
| 2 |
Zavier Scott |
RB |
4 |
4 |
1.0 |
0 |
5 |
Week RS8 • 2025-10-26 • vs NYG (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tyrone Tracy Jr. |
RB |
10 |
39 |
3.9 |
0 |
6 |
| 2 |
Devin Singletary |
RB |
2 |
0 |
0.0 |
0 |
3 |
Week RS10 • 2025-11-10 • vs GB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Josh Jacobs |
RB |
21 |
74 |
3.5 |
1 |
11 |
| 2 |
Emanuel Wilson |
RB |
1 |
2 |
2.0 |
0 |
2 |
Week RS11 • 2025-11-16 • vs DET (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jahmyr Gibbs |
RB |
12 |
39 |
3.3 |
0 |
11 |
| 2 |
David Montgomery |
RB |
6 |
27 |
4.5 |
0 |
7 |
Week RS12 • 2025-11-23 • vs DAL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Javonte Williams |
RB |
20 |
87 |
4.4 |
0 |
20 |
| 2 |
Malik Davis |
RB |
3 |
24 |
8.0 |
0 |
21 |
Week RS14 • 2025-12-08 • vs LAC (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Omarion Hampton |
RB |
13 |
56 |
4.3 |
0 |
18 |
| 2 |
Kimani Vidal |
RB |
14 |
44 |
3.1 |
0 |
8 |
Week RS15 • 2025-12-14 • vs LV (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Ashton Jeanty |
RB |
9 |
35 |
3.9 |
0 |
11 |
| 2 |
Dylan Laube |
RB |
2 |
4 |
2.0 |
0 |
3 |
