Week RS1 • 2025-09-07 • vs DEN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
RJ Harvey |
RB |
6 |
70 |
11.7 |
0 |
50 |
Week RS2 • 2025-09-14 • vs LAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
17 |
66 |
3.9 |
0 |
15 |
| 2 |
Blake Corum |
RB |
5 |
44 |
8.8 |
1 |
15 |
Week RS3 • 2025-09-21 • vs IND (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jonathan Taylor |
RB |
17 |
102 |
6.0 |
3 |
46 |
| 2 |
Tyler Goodson |
RB |
2 |
6 |
3.0 |
0 |
4 |
Week RS4 • 2025-09-28 • vs HOU (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
17 |
69 |
4.1 |
1 |
18 |
| 2 |
Nick Chubb |
RB |
13 |
47 |
3.6 |
0 |
11 |
Week RS5 • 2025-10-05 • vs ARI (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Michael Carter |
RB |
18 |
51 |
2.8 |
1 |
7 |
| 2 |
Emari Demercado |
RB |
3 |
81 |
27.0 |
0 |
71 |
Week RS6 • 2025-10-12 • vs LV (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Ashton Jeanty |
RB |
23 |
75 |
3.3 |
1 |
13 |
| 2 |
Raheem Mostert |
RB |
5 |
-4 |
-0.8 |
0 |
3 |
Week RS7 • 2025-10-19 • vs NE (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
TreVeyon Henderson |
RB |
2 |
5 |
2.5 |
0 |
3 |
| 2 |
Rhamondre Stevenson |
RB |
18 |
88 |
4.9 |
1 |
16 |
Week RS8 • 2025-10-26 • vs IND (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jonathan Taylor |
RB |
12 |
153 |
12.8 |
2 |
80 |
| 2 |
Ameer Abdullah |
RB |
2 |
5 |
2.5 |
0 |
3 |
Week RS11 • 2025-11-16 • vs HOU (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
18 |
44 |
2.4 |
0 |
12 |
| 2 |
Nick Chubb |
RB |
3 |
17 |
5.7 |
0 |
8 |
Week RS12 • 2025-11-23 • vs SEA (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
11 |
71 |
6.5 |
0 |
19 |
| 2 |
Zach Charbonnet |
RB |
6 |
35 |
5.8 |
1 |
13 |
Week RS13 • 2025-11-30 • vs JAX (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
12 |
28 |
2.3 |
0 |
6 |
| 2 |
Bhayshul Tuten |
RB |
8 |
17 |
2.1 |
1 |
7 |
Week RS14 • 2025-12-07 • vs CLE (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Quinshon Judkins |
RB |
14 |
26 |
1.9 |
0 |
14 |
| 2 |
Dylan Sampson |
RB |
2 |
4 |
2.0 |
0 |
4 |
Week RS15 • 2025-12-14 • vs SF (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Christian McCaffrey |
RB |
22 |
73 |
3.3 |
1 |
9 |
| 2 |
Brian Robinson Jr. |
RB |
9 |
21 |
2.3 |
0 |
6 |
