Week RS1 • 2025-09-07 • vs GB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Josh Jacobs |
RB |
19 |
66 |
3.5 |
1 |
15 |
| 2 |
Emanuel Wilson |
RB |
1 |
4 |
4.0 |
0 |
4 |
Week RS2 • 2025-09-14 • vs CHI (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
D'Andre Swift |
RB |
12 |
63 |
5.3 |
1 |
20 |
| 2 |
Kyle Monangai |
RB |
7 |
28 |
4.0 |
0 |
10 |
Week RS3 • 2025-09-22 • vs BAL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Derrick Henry |
RB |
12 |
50 |
4.2 |
1 |
28 |
Week RS4 • 2025-09-28 • vs CLE (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Quinshon Judkins |
RB |
21 |
82 |
3.9 |
1 |
11 |
| 2 |
Dylan Sampson |
RB |
1 |
-2 |
-2.0 |
0 |
-2 |
Week RS5 • 2025-10-05 • vs CIN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chase Brown |
RB |
8 |
27 |
3.4 |
0 |
6 |
| 2 |
Samaje Perine |
RB |
4 |
27 |
6.8 |
0 |
10 |
Week RS6 • 2025-10-12 • vs KC (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Isiah Pacheco |
RB |
12 |
51 |
4.3 |
0 |
11 |
| 2 |
Kareem Hunt |
RB |
6 |
23 |
3.8 |
0 |
10 |
Week RS7 • 2025-10-20 • vs TB (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rachaad White |
RB |
10 |
38 |
3.8 |
0 |
7 |
| 2 |
Sean Tucker |
RB |
1 |
4 |
4.0 |
0 |
4 |
Week RS10 • 2025-11-09 • vs WSH (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chris Rodriguez Jr. |
RB |
6 |
16 |
2.7 |
1 |
9 |
| 2 |
Jacory Croskey-Merritt |
RB |
11 |
30 |
2.7 |
0 |
6 |
Week RS11 • 2025-11-16 • vs PHI (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Saquon Barkley |
RB |
26 |
83 |
3.2 |
0 |
14 |
| 2 |
Tank Bigsby |
RB |
4 |
34 |
8.5 |
0 |
17 |
Week RS12 • 2025-11-23 • vs NYG (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tyrone Tracy Jr. |
RB |
20 |
62 |
3.1 |
0 |
11 |
| 2 |
Devin Singletary |
RB |
14 |
47 |
3.4 |
0 |
13 |
Week RS13 • 2025-11-27 • vs GB (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Josh Jacobs |
RB |
17 |
83 |
4.9 |
0 |
29 |
| 2 |
Emanuel Wilson |
RB |
4 |
14 |
3.5 |
0 |
5 |
Week RS15 • 2025-12-14 • vs LAR (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
15 |
78 |
5.2 |
2 |
19 |
| 2 |
Blake Corum |
RB |
11 |
71 |
6.5 |
1 |
24 |
