Week RS1 • 2025-09-05 • vs KC (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Isiah Pacheco |
RB |
5 |
25 |
5.0 |
0 |
10 |
| 2 |
Kareem Hunt |
RB |
5 |
16 |
3.2 |
0 |
6 |
Week RS2 • 2025-09-15 • vs LV (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Ashton Jeanty |
RB |
11 |
43 |
3.9 |
0 |
13 |
| 2 |
Zamir White |
RB |
2 |
-2 |
-1.0 |
0 |
3 |
Week RS3 • 2025-09-21 • vs DEN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
RJ Harvey |
RB |
2 |
2 |
1.0 |
0 |
4 |
Week RS4 • 2025-09-28 • vs NYG (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Devin Singletary |
RB |
7 |
28 |
4.0 |
0 |
8 |
Week RS5 • 2025-10-05 • vs WSH (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chris Rodriguez Jr. |
RB |
5 |
7 |
1.4 |
0 |
3 |
| 2 |
Jacory Croskey-Merritt |
RB |
14 |
111 |
7.9 |
2 |
27 |
Week RS6 • 2025-10-12 • vs MIA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
De'Von Achane |
RB |
16 |
128 |
8.0 |
2 |
49 |
| 2 |
Ollie Gordon II |
RB |
2 |
1 |
0.5 |
0 |
3 |
Week RS7 • 2025-10-19 • vs IND (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jonathan Taylor |
RB |
16 |
94 |
5.9 |
3 |
23 |
| 2 |
Ameer Abdullah |
RB |
2 |
19 |
9.5 |
0 |
14 |
Week RS10 • 2025-11-09 • vs PIT (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jaylen Warren |
RB |
14 |
70 |
5.0 |
0 |
14 |
| 2 |
Kaleb Johnson |
RB |
2 |
3 |
1.5 |
0 |
5 |
Week RS11 • 2025-11-16 • vs JAX (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
19 |
73 |
3.8 |
2 |
13 |
| 2 |
Bhayshul Tuten |
RB |
15 |
74 |
4.9 |
1 |
15 |
Week RS13 • 2025-11-30 • vs LV (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Ashton Jeanty |
RB |
15 |
31 |
2.1 |
0 |
9 |
| 2 |
Raheem Mostert |
RB |
1 |
6 |
6.0 |
0 |
6 |
Week RS14 • 2025-12-08 • vs PHI (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Saquon Barkley |
RB |
20 |
122 |
6.1 |
1 |
52 |
| 2 |
Tank Bigsby |
RB |
1 |
4 |
4.0 |
0 |
4 |
Week RS15 • 2025-12-14 • vs KC (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Isiah Pacheco |
RB |
11 |
21 |
1.9 |
0 |
7 |
| 2 |
Kareem Hunt |
RB |
6 |
12 |
2.0 |
0 |
4 |
