Week RS1 • 2025-09-07 • vs PIT (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jaylen Warren |
RB |
11 |
37 |
3.4 |
0 |
9 |
| 2 |
Kenneth Gainwell |
RB |
7 |
19 |
2.7 |
0 |
6 |
Week RS2 • 2025-09-14 • vs BUF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
James Cook |
RB |
21 |
132 |
6.3 |
2 |
44 |
| 2 |
Ray Davis |
RB |
9 |
24 |
2.7 |
0 |
8 |
Week RS3 • 2025-09-21 • vs TB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bucky Irving |
RB |
25 |
66 |
2.6 |
0 |
16 |
| 2 |
Rachaad White |
RB |
5 |
12 |
2.4 |
0 |
7 |
Week RS4 • 2025-09-29 • vs MIA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
De'Von Achane |
RB |
20 |
99 |
5.0 |
1 |
21 |
| 2 |
Ollie Gordon II |
RB |
6 |
10 |
1.7 |
0 |
7 |
Week RS5 • 2025-10-05 • vs DAL (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Javonte Williams |
RB |
16 |
135 |
8.4 |
1 |
66 |
| 2 |
Jaydon Blue |
RB |
4 |
7 |
1.8 |
0 |
6 |
Week RS6 • 2025-10-12 • vs DEN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
RJ Harvey |
RB |
2 |
4 |
2.0 |
0 |
2 |
| 2 |
Jaleel McLaughlin |
RB |
1 |
0 |
0.0 |
0 |
0 |
Week RS7 • 2025-10-19 • vs CAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rico Dowdle |
RB |
17 |
79 |
4.6 |
0 |
13 |
| 2 |
Chuba Hubbard |
RB |
14 |
31 |
2.2 |
0 |
11 |
Week RS8 • 2025-10-26 • vs CIN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chase Brown |
RB |
12 |
73 |
6.1 |
1 |
22 |
| 2 |
Samaje Perine |
RB |
9 |
94 |
10.4 |
1 |
32 |
Week RS10 • 2025-11-09 • vs CLE (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Quinshon Judkins |
RB |
22 |
75 |
3.4 |
0 |
11 |
| 2 |
Dylan Sampson |
RB |
2 |
-4 |
-2.0 |
0 |
3 |
Week RS11 • 2025-11-13 • vs NE (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
TreVeyon Henderson |
RB |
19 |
62 |
3.3 |
2 |
9 |
| 2 |
D'Ernest Johnson |
RB |
3 |
6 |
2.0 |
0 |
5 |
Week RS12 • 2025-11-23 • vs BAL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Derrick Henry |
RB |
21 |
64 |
3.0 |
2 |
17 |
| 2 |
Keaton Mitchell |
RB |
2 |
10 |
5.0 |
0 |
9 |
Week RS13 • 2025-11-30 • vs ATL (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bijan Robinson |
RB |
23 |
142 |
6.2 |
1 |
26 |
| 2 |
Tyler Allgeier |
RB |
8 |
20 |
2.5 |
1 |
12 |
Week RS14 • 2025-12-07 • vs MIA (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
De'Von Achane |
RB |
7 |
92 |
13.1 |
1 |
39 |
| 2 |
Jaylen Wright |
RB |
24 |
107 |
4.5 |
1 |
12 |
Week RS15 • 2025-12-14 • vs JAX (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
12 |
32 |
2.7 |
0 |
8 |
| 2 |
Bhayshul Tuten |
RB |
1 |
7 |
7.0 |
0 |
7 |
