Week RS1 • 2025-09-07 • vs NYJ (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Breece Hall |
RB |
19 |
107 |
5.6 |
0 |
18 |
| 2 |
Isaiah Davis |
RB |
2 |
18 |
9.0 |
0 |
15 |
Week RS2 • 2025-09-14 • vs SEA (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
13 |
105 |
8.1 |
1 |
20 |
| 2 |
Zach Charbonnet |
RB |
15 |
10 |
0.7 |
0 |
6 |
Week RS3 • 2025-09-21 • vs NE (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
TreVeyon Henderson |
RB |
11 |
28 |
2.5 |
0 |
5 |
| 2 |
Rhamondre Stevenson |
RB |
4 |
18 |
4.5 |
0 |
10 |
Week RS4 • 2025-09-28 • vs MIN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jordan Mason |
RB |
16 |
57 |
3.6 |
0 |
9 |
| 2 |
Zavier Scott |
RB |
2 |
1 |
0.5 |
0 |
2 |
Week RS6 • 2025-10-12 • vs CLE (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Quinshon Judkins |
RB |
12 |
36 |
3.0 |
0 |
6 |
| 2 |
Dylan Sampson |
RB |
3 |
12 |
4.0 |
0 |
7 |
Week RS7 • 2025-10-16 • vs CIN (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chase Brown |
RB |
11 |
108 |
9.8 |
0 |
37 |
| 2 |
Samaje Perine |
RB |
7 |
31 |
4.4 |
0 |
9 |
Week RS8 • 2025-10-26 • vs GB (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Josh Jacobs |
RB |
13 |
33 |
2.5 |
1 |
6 |
| 2 |
Emanuel Wilson |
RB |
11 |
61 |
5.5 |
0 |
15 |
Week RS10 • 2025-11-09 • vs LAC (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kimani Vidal |
RB |
25 |
95 |
3.8 |
1 |
12 |
Week RS11 • 2025-11-16 • vs CIN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Chase Brown |
RB |
18 |
99 |
5.5 |
0 |
35 |
| 2 |
Tahj Brooks |
RB |
1 |
5 |
5.0 |
0 |
5 |
Week RS12 • 2025-11-23 • vs CHI (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
D'Andre Swift |
RB |
8 |
15 |
1.9 |
0 |
4 |
| 2 |
Kyle Monangai |
RB |
12 |
48 |
4.0 |
1 |
12 |
Week RS13 • 2025-11-30 • vs BUF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
James Cook III |
RB |
32 |
144 |
4.5 |
0 |
31 |
| 2 |
Ray Davis |
RB |
9 |
62 |
6.9 |
0 |
15 |
Week RS14 • 2025-12-07 • vs BAL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Derrick Henry |
RB |
25 |
94 |
3.8 |
0 |
19 |
| 2 |
Keaton Mitchell |
RB |
6 |
76 |
12.7 |
0 |
55 |
Week RS15 • 2025-12-15 • vs MIA (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
De'Von Achane |
RB |
12 |
60 |
5.0 |
0 |
15 |
| 2 |
Jaylen Wright |
RB |
1 |
2 |
2.0 |
0 |
2 |
