Week RS1 • 2025-09-07 • vs SEA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
10 |
20 |
2.0 |
0 |
8 |
| 2 |
Zach Charbonnet |
RB |
12 |
47 |
3.9 |
1 |
7 |
Week RS2 • 2025-09-14 • vs NO (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Alvin Kamara |
RB |
21 |
99 |
4.7 |
0 |
15 |
Week RS3 • 2025-09-21 • vs ARI (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Emari Demercado |
RB |
2 |
0 |
0.0 |
0 |
1 |
Week RS4 • 2025-09-28 • vs JAX (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Travis Etienne Jr. |
RB |
19 |
124 |
6.5 |
1 |
48 |
| 2 |
Bhayshul Tuten |
RB |
4 |
14 |
3.5 |
0 |
8 |
Week RS5 • 2025-10-02 • vs LAR (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
14 |
65 |
4.6 |
0 |
20 |
| 2 |
Blake Corum |
RB |
1 |
13 |
13.0 |
0 |
13 |
Week RS6 • 2025-10-12 • vs TB (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rachaad White |
RB |
17 |
65 |
3.8 |
1 |
10 |
| 2 |
Sean Tucker |
RB |
6 |
25 |
4.2 |
1 |
9 |
Week RS7 • 2025-10-19 • vs ATL (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bijan Robinson |
RB |
14 |
40 |
2.9 |
0 |
8 |
| 2 |
Tyler Allgeier |
RB |
4 |
16 |
4.0 |
0 |
7 |
Week RS8 • 2025-10-26 • vs HOU (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
11 |
62 |
5.6 |
0 |
23 |
| 2 |
Nick Chubb |
RB |
17 |
56 |
3.3 |
0 |
9 |
Week RS10 • 2025-11-09 • vs LAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
14 |
73 |
5.2 |
2 |
12 |
| 2 |
Blake Corum |
RB |
13 |
56 |
4.3 |
0 |
15 |
Week RS11 • 2025-11-16 • vs ARI (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bam Knight |
RB |
5 |
24 |
4.8 |
1 |
7 |
| 2 |
Emari Demercado |
RB |
5 |
8 |
1.6 |
0 |
5 |
Week RS12 • 2025-11-24 • vs CAR (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Rico Dowdle |
RB |
6 |
38 |
6.3 |
0 |
17 |
| 2 |
Chuba Hubbard |
RB |
3 |
16 |
5.3 |
0 |
10 |
Week RS13 • 2025-11-30 • vs CLE (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Quinshon Judkins |
RB |
23 |
91 |
4.0 |
0 |
17 |
| 2 |
Dylan Sampson |
RB |
4 |
23 |
5.8 |
0 |
9 |
Week RS15 • 2025-12-14 • vs TEN (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Tony Pollard |
RB |
14 |
104 |
7.4 |
1 |
22 |
| 2 |
Tyjae Spears |
RB |
3 |
34 |
11.3 |
0 |
20 |
