San Francisco 49ers Injuries

Showing latest report per player. Last update in DB: Sep 20
IR (13) O (2) D (0) Q (19) PUP (0) SUS (0) NA (0)

Injured Reserve 13

Brett Toth
Brett Toth C IR
Injured Reserve
Toth missed most of training camp due to a concussion, an issue which prevented him from playing in the Eagles' wild-card loss to the 49ers in January. Because there was no designation to return attached to his placement on IR, Toth will be required to miss the entire 2026 season unless he reaches an injury settlement with the 49ers.
Reported: Aug 31
Nate Hobbs
Nate Hobbs CB IR
Injured Reserve
Hobbs injured his groin during a joint practice with the Titans in mid-August, and it was reported at the time by Matt Maiocco of NBC Sports Bay Area that the 2021 fifth-rounder would miss a few weeks. Hobbs will be required to miss at least four games, so the earliest he can make his 2026 regular-season debut is Week 5 against the Seahawks on Sunday, Oct. 11. With Hobbs sidelined, Siran Neal and Jack Jones will serve as the 49ers' depth options at cornerback behind Renardo Green (hamstring) and Deommodore Lenoir.
Reported: Sep 01
Mikail Kamara
Injured Reserve
Matt Maiocco of NBC Sports Bay Area reports Kamara suffered a torn ACL. The undrafted free agent out of Indiana will now spend the duration of the 2026 season on IR unless he and the 49ers reach an injury settlement.
Reported: Aug 03
Victor Dimukeje
Injured Reserve
The linebacker signed with San Francisco on Aug. 17 and appeared to be healthy again after missing the end of the 2025 campaign with a knee issue. It's unclear if this injury is related. Dimukeje would need to reach an injury settlement with the 49ers to have a chance to play in 2026.
Reported: Aug 27
Alfred Collins
Injured Reserve
This move was anticipated, as Collins is set to miss the entire 2026 campaign as a result of tearing his patellar tendon during practice Tuesday. Osa Odighizuwa, CJ West and Gracen Halton should get plenty of reps at defensive tackle with Collins and Sam Okuayinonu (foot) sidelined.
Reported: Sep 10
Sam Okuayinonu
Injured Reserve
Head coach Kyle Shanahan said Monday he hopes Okuayinonu can return near the end of the regular season, but it is unclear quite how long the recovery process will take. Okuayinonu previously had a plate in his foot, and the break occurred when it was stepped on during practice.
Reported: Sep 07
Nick Martin
Nick Martin LB IR
Injured Reserve
Martin had been dealing with a hamstring injury recently that will now force him to miss the start of the regular season. The 23-year-old will be sidelined for at least four games before he's eligible to be designated to return.
Reported: Sep 01
Austen Pleasants
Injured Reserve
Pleasants sustained a knee injury during the 49ers' preseason game against the Chargers on Aug. 20. The injury is severe enough for 29-year-old offensive tackle to open the year on IR, meaning he'll be forced to miss at least the first four games of the regular season.
Reported: Aug 31
Nick Zakelj
Nick Zakelj OT IR
Injured Reserve
The nature of Zakelj's injury is unclear, as is when he exactly picked up the injury. However, by being placed on IR without a designation to return, the 2022 sixth-rounder will be forced to miss the entire upcoming season unless he reached an injury settlement with San Francisco.
Reported: Aug 31
Jake Tonges
Jake Tonges TE IR
Injured Reserve
The team placed Tonges on injured reserve earlier Wednesday, and now it's official that he will miss the rest of the season. Tonges suffered an MCL tear in the season opener against the Rams. Jack Stoll was signed to the practice squad to add depth, and Luke Farrell now projects to be the second tight end behind George Kittle.
Reported: Sep 16
Christian Kirk
Injured Reserve
Kirk missed the entirety of the preseason after suffering a calf injury at practice July 26, and he will now be forced to sit out at least four contests to open the regular season. The wide receiver signed with San Francisco in the offseason, and he was expected to occupy a prominent role on offense. In his absence, rookie wideout De'Zhaun Stribling (shoulder) will have a chance to be an impact player in his NFL debut Week 1 against the Rams in Australia.
Reported: Aug 30
De'Zhaun Stribling
Injured Reserve
Stribling suffered what appeared to be a serious non-contact injury during the 49ers' Week 1 win against the Rams in Melbourne, Australia, but afterward tests revealed that his left Achilles was intact, and eventually he was diagnosed with a deltoid sprain of his left ankle. After undergoing surgery, he's expected to miss roughly 10 weeks, meaning a move to IR was inevitable. At least during the initial weeks of Stribling's absence, Mike Evans, Deebo Samuel, Demarcus Robinson, Jacob Cowing, Jordan Watkins and KhaDarel Hodge will handle WR duties for San Francisco.
Reported: Sep 19
Ricky Pearsall
Injured Reserve
The procedure typically carries a wide-ranging recovery timeline of 6-to-12 months, so while Pearsall will be ruled out for the season, it's not clear if he'll be available for the start of the 49ers' offseason program next spring or the start of training camp next summer. The wideout will wind up having played in just 20 of a possible 51 regular-season contests and one of two playoff games through his first three NFL campaigns, missing time as a rookie while recovering from a gunshot wound to the chest before being hampered by the PCL injury off and on in 2025. He'll turn 27 in September and will be entering the final season of his rookie contract in 2027.
Reported: Aug 13

Out 2

Mykel Williams
Out
Williams is still recovering from a torn ACL that he suffered in November 2025, and he was unable to practice or play during the preseason. The 22-year-old will now be forced to miss at least four contests to open the regular season, and the earliest he'll be able to return to action is Week 5 against the Seahawks on Oct. 11.
Reported: Aug 31
Isaac Guerendo
Out
Guerendo spent all of training camp on the active/PUP list and is seemingly not ready to take the field, so he will remain on PUP and will miss at least the first four weeks of the season. As such, Kaelon Black and Jordan James will open as the top two options behind starter Christian McCaffrey (undisclosed).
Reported: Aug 30

Doubtful 0

No players in this category.

Questionable 19

Ephesians Prysock
Questionable
The cornerback recorded one solo tackle before exiting. Prysock was selected by the 49ers in the fourth round of April's draft and is competing for a depth role on defense.
Reported: Aug 27
Jakob Robinson
Questionable
Robinson logged 45 defensive snaps over the course of the night, playing a whopping 74 percent of the 49ers' total defensive reps. The fourth-string cornerback may get a chance to play during the regular season if the injuries to Jack Jones (hand) and Nate Hobbs (groin) persist longer than expected.
Reported: Aug 14
Upton Stout
Questionable
Per Wagoner, coach Kyle Shanahan said Tuesday that he expects Stout to be back at practice next week before the team goes to Australia for its regular-season debut against the Rams. For now, free-agent acquisition Jack Jones and Darrell Luter are candidates to take any reps in the secondary left on the table.
Reported: Aug 25
Keion White
Questionable
questionable
Reported: Sep 16
Nick Bosa
Nick Bosa DE Q
Questionable
Bosa has been continuing the rehab on his right knee after undergoing surgery for a torn ACL last September. The star edge rusher traveled with the 49ers to Melbourne, Australia ahead of Thursday's season opener, but his status had been uncertain entering the week. Morris seemed to confirm that Bosa will play while speaking to reporters in Melbourne on Tuesday (local time), saying of Bosa, "Oh, he's going out there. Whatever you want to say, he's going. He'll be there. We're not hiding that."
Reported: Sep 07
Romello Height
Questionable
Height likely picked up an injury during Saturday's practice session. The third-round rookie tallied one tackle in Thursday's preseason win over the Chargers and is set to be a reserve piece on the edge throughout the 2026 season.
Reported: Aug 23
Osa Odighizuwa
Questionable
Odighizuwa missed Wednesday's practice, but was promptly back in action for Thursday's session. The defensive end reclaimed his snaps with the first-team defense and looks to be over whatever was previously ailing him.
Reported: Aug 06
Robert Jones
Questionable
Per Wagoner, coach Kyle Shanahan said Tuesday that Jones has a chance to return to the field next week. For now, 2025 seventh-rounder Connor Colby could get some reps with the first-team offensive line.
Reported: Aug 25
Eddy Pineiro
Questionable
The 49ers ended up trying out two kickers Saturday -- Greg Joseph and Younghoe Koo -- but won't sign either of them to the practice squad, meaning Pineiro will handle his normal placekicking duties in Week 2. In 15 regular-season games with San Francisco going back to the 2025 campaign, Pineiro has netted 30 of 32 field-goal attempts and 37 of 41 point-after tries.
Reported: Sep 19
Kurtis Rourke
Questionable
Rourke suffered three broken ribs during San Francisco's preseason opener versus the Titans, but it seems like the injury may not keep the quarterback on the sidelines much longer. Until Rourke is healthy again, Adrian Martinez still projects as the 49ers' third signal-caller behind Brock Purdy and Mac Jones.
Reported: Aug 25
Christian McCaffrey
Questionable
McCaffrey wasn't spotted taking part in the early portion of practice Monday, so his presence on the field in full uniform Tuesday is a promising sign for his potential availability for the 49ers' season opener against the Rams. It's been a bit of a mysterious several weeks for McCaffrey, as he was described as dealing with "tightness" in early August and didn't play at all in the preseason while being an inconsistent participant in team drills. San Francisco's injury reports this week should shed some light on McCaffrey's status for the matchup against Los Angeles, but to this point he seems more likely than not to play in that contest.
Reported: Sep 08
Jordan James
Questionable
James fractured his rib in late July and has still not recovered from the issue. Once healthy, the running back will have a chance to earn complementary work behind Christian McCaffrey (undisclosed), though as long as McCaffrey is available this season, he'll be busy, leaving limited touches for his backups. With fellow RB Kaelon Black (thigh) also not participating in Thursday's game, Patrick Taylor, Sincere McCormick, Khalil Herbert and Zamir White are on hand to absorb Thursday's carries in an effort to climb a depth chart littered with injuries before cutdown day.
Reported: Aug 13
Kaelon Black
Questionable
Black popped up on Thursday's injury report as a limited participant due to a groin injury, and he was given a questionable designation after getting in another limited session Friday. While there is reason to believe he will take the field Sunday, his availability will not be confirmed until the 49ers release their inactives 90 minutes before Sunday's 4:25 p.m. ET kickoff.
Reported: Sep 20
Brayden Willis
Questionable
The tight end caught one pass for seven yards before leaving the game. The 2023 seventh-round pick is fighting for a roster spot with backups Jake Tonges and Luke Farrell Willis has seen action in each of the last three seasons with the 49ers, primarily on special teams.
Reported: Aug 27
George Kittle
Questionable
Kittle operated with a cap on his practice reps last week before returning to action just nine months removed from tearing his right Achilles in a wild-card win at Philadelphia. In the 49ers' Week 1 victory against the Rams in Melbourne, Australia, he started, played 30 of 65 offensive snaps and gathered in two of five targets for 12 yards. San Francisco may continue to take it easy on Kittle in the early going with the long term in mind, but his status for game days doesn't appear to be in any question.
Reported: Sep 16
Jacob Cowing
Questionable
Per Wagoner, coach Kyle Shanahan said Tuesday that he expects Cowing to return to practice next week before the team travels to Australia for its regular-season debut against the Rams. In the meantime, 2025 fourth-rounder Jordan Watkins could be called on to perform punt-return duties with the first team.
Reported: Aug 25
Mike Evans
Mike Evans WR Q
Questionable
Wagoner notes that linebacker Nick Bosa (knee) and running back Christian McCaffrey (undisclosed) were the only 49ers players who didn't appear to be mixing into team drills during the open portion of practice, so Evans appears likely to have been at least a limited participant in Monday's session. The 49ers will release their first injury report of the season later Monday, when the extent of Evans' practice participation will be revealed. Evans had his practice activity managed for much of training camp while he contended with a minor quadriceps strain and, more recently, an adductor injury.
Reported: Sep 07

Physically Unable to Perform 0

No players in this category.

Suspended 0

No players in this category.

Other / NA 0

No players in this category.