Injured reserve
Robinson (forearm) was placed on injured reserve Tuesday.
Reported: Aug 27
San Francisco 49ers Injuries
Showing latest report per player. Last update in DB: Dec 31
IR (14)
O (18)
D (0)
Q (23)
PUP (0)
SUS (0)
NA (0)
Injured Reserve 14
Injured reserve
Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log.
Reported: May 13
Injured reserve
The 49ers placed Williams (knee) on injured reserve Saturday.
Reported: Nov 08
Injured reserve
Bosa (knee) underwent surgery to address his torn ACL on Friday, Cam Inman of The San Jose Mercury News reports.
Reported: Sep 26
Injured reserve
Jackson (undisclosed) was discharged from the hospital and returned to the 49ers' training camp Monday, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Jul 29
Injured reserve
Gross-Matos (hamstring/knee) is officially listed as questionable for Monday's game against the Colts, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Dec 20, 2025
Injured reserve
The 49ers placed Bartch (foot) on injured reserve Monday.
Reported: Dec 08
Injured reserve
Warner (ankle) is ahead of schedule in his recovery and could be a candidate to return to action if the 49ers make a deep playoff run, Ian Rapoport and Mike Garafolo of NFL Network report.
Reported: Dec 27
Injured reserve
The 49ers placed Martin (concussion) on injured reserve Saturday.
Reported: Dec 20
Injured reserve
The 49ers moved Bethune (groin) to injured reserve Wednesday.
Reported: Jan 07
Injured reserve
Taylor will undergo season-ending surgery to repair a fracture in his shoulder, Nick Wagoner of ESPN.com reports.
Reported: Aug 19
Injured reserve
Kittle (hamstring) practiced in a limited capacity Thursday, Cam Inman of The San Jose Mercury News reports.
Reported: Oct 16, 2025
Injured reserve
San Francisco head coach Kyle Shanahan said Friday that Cowing (hamstring) could have his 21-day practice window opened during Week 18 prep, Matt Barrows of The Athletic reports.
Reported: Dec 31
Injured reserve
The 49ers placed Taylor (undisclosed) on injured reserve Tuesday.
Reported: Jun 03
Out 18
Out
Robinson (coach's decision) is inactive for Saturday night's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
Reported: Jan 03
Out
Pineiro (hamstring) is expected to return to action following the 49ers' bye week in Week 14, Matt Barrows of The Athletic reports.
Reported: Dec 01, 2025
Out
Rourke (knee) will remain on the 49ers' reserve/non-football injury list for the rest of the 2025 season, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Dec 29
Out
James (coach's decision) is inactive for Sunday's game against the Cardinals, Briana Jeannel of the 49ers' official site reports.
Reported: Nov 16, 2025
Out
Mustapha (knee) practiced fully Wednesday, Eric Branch of the San Francisco Chronicle reports.
Reported: Oct 08, 2025
Out
The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.
Reported: Dec 13
Out
Watkins (coach's decision) is inactive for Sunday's game against the Cardinals, Briana Jeannel of the 49ers' official site reports.
Reported: Nov 16, 2025
Doubtful 0
No players in this category.
Questionable 23
Questionable
Lenoir (quadriceps) is listed as questionable for Sunday's game against the Texans, Nick Wagoner of ESPN.com reports.
Reported: Oct 24, 2025
Questionable
Green (foot) is listed as questionable for Sunday's wild-card road game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Jan 09
Questionable
Stout (shoulder) was a limited participant at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Reported: Oct 29, 2025
Questionable
Huff (hamstring) was a limited participant in practice for the second day in a row Thursday, Matt Barrows of The Athletic reports.
Reported: Nov 06, 2025
Questionable
White (groin/hamstring) is listed as questionable ahead of Sunday's wild-card matchup with the Eagles, Noah Furtado of the San Francisco Chronicle reports.
Reported: Jan 09
Questionable
Collins (hip) was a limited practice participant Wednesday, Cam Inman of The San Jose Mercury News reports.
Reported: Nov 12, 2025
Questionable
Elliott (knee) is expected to practice this week, Matt Barrows of The Athletic reports.
Reported: Dec 15, 2025
Questionable
Davis (ankle) was a limited participant in practice Thursday, Matt Barrows of The Athletic reports.
Reported: Nov 06, 2025
Questionable
Okuayinonu (ankle) is expected to return to practice during Week 16 prep, Matt Barrows of The Athletic reports.
Reported: Dec 15, 2025
Questionable
Juszczyk is dealing with a rib fracture ahead of the 49ers' bye week, David Lombardi of SFStandard.com reports.
Reported: Dec 01, 2025
Questionable
Winters (ankle) is listed as questionable for Sunday's wild-card road game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Jan 09
Questionable
Gifford (quadriceps) is listed as questionable for Sunday's wild-card game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Jan 09
Questionable
Burford (knee) was activated from injured reserve Saturday.
Reported: Nov 01, 2025
Questionable
Williams (hamstring) is listed as questionable for Sunday's wild-card road game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Reported: Jan 09
Questionable
San Francisco head coach Kyle Shanahan relayed that Purdy suffered a "stinger" after taking a hard hit to his left shoulder on the 49ers' final offensive play of Saturday's 13-3 loss to the Seahawks, Noah Furtado and Eric Branch of the San Francisco Chronicle report. "It's just I got hit, and the left shoulder sort of lit up," Purdy said after the contest. "I feel good right now. We'll see how I feel [Sunday]."
Reported: Jan 04
Questionable
Coach Kyle Shanahan said Monday that Jones suffered a bruised knee during Sunday's 26-15 loss at Houston and is "day-to-day," David Lombardi of SFStandard.com reports.
Reported: Oct 27, 2025
Questionable
Although he was added to the 49ers' injury report Saturday, McCaffrey (back) is expected to play against the Titans on Sunday, Adam Schefter of ESPN reports.
Reported: Dec 13, 2025
Questionable
Jennings (ankle/rib/shoulder) was a limited practice participant Thursday, Cam Inman of The San Jose Mercury News reports.
Reported: Oct 16, 2025
Questionable
Valdes-Scantling missed Thursday's practice due to a calf injury, Cam Inman of The San Jose Mercury News reports.
Reported: Oct 16, 2025
Questionable
Pearsall (knee/ankle) is listed as questionable for Sunday's game at Philadelphia despite not practicing at all this week, Noah Furtado of the San Francisco Chronicle reports.
Reported: Jan 09
Questionable
Moore (ankle) was a limited participant in practice Thursday after missing Wednesday's session, Cam Inman of The San Jose Mercury News reports.
Reported: Oct 16, 2025
Physically Unable to Perform 0
No players in this category.
Suspended 0
No players in this category.
Other / NA 0
No players in this category.
Dec 31
Injured reserve
San Francisco head coach Kyle Shanahan said Friday that Cowing (hamstring) could have his 21-day practice window opened during Week 18 prep, Matt Barrows of The Athletic reports.
Dec 29
Out
Rourke (knee) will remain on the 49ers' reserve/non-football injury list for the rest of the 2025 season, Matt Maiocco of NBC Sports Bay Area reports.
Dec 27
Injured reserve
Warner (ankle) is ahead of schedule in his recovery and could be a candidate to return to action if the 49ers make a deep playoff run, Ian Rapoport and Mike Garafolo of NFL Network report.
Dec 20
Dec 13
Out
The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.
Dec 08
Nov 08
Sep 26
Injured reserve
Bosa (knee) underwent surgery to address his torn ACL on Friday, Cam Inman of The San Jose Mercury News reports.
Aug 27
Aug 19
Injured reserve
Taylor will undergo season-ending surgery to repair a fracture in his shoulder, Nick Wagoner of ESPN.com reports.
Jul 29
Injured reserve
Jackson (undisclosed) was discharged from the hospital and returned to the 49ers' training camp Monday, Matt Maiocco of NBC Sports Bay Area reports.
Jun 03
Injured reserve
The 49ers placed Taylor (undisclosed) on injured reserve Tuesday.
May 13
Injured reserve
Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log.
Jan 09
Questionable
Winters (ankle) is listed as questionable for Sunday's wild-card road game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Injured reserve
Cowing (hamstring) is listed as questionable for Sunday's wild-card game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports, but the wide receiver remains on injured reserve.
Questionable
White (groin/hamstring) is listed as questionable ahead of Sunday's wild-card matchup with the Eagles, Noah Furtado of the San Francisco Chronicle reports.
Questionable
Gifford (quadriceps) is listed as questionable for Sunday's wild-card game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Green (foot) is listed as questionable for Sunday's wild-card road game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Pearsall (knee/ankle) is listed as questionable for Sunday's game at Philadelphia despite not practicing at all this week, Noah Furtado of the San Francisco Chronicle reports.
Questionable
Williams (hamstring) is listed as questionable for Sunday's wild-card road game against the Eagles, Matt Maiocco of NBC Sports Bay Area reports.
Jan 08
Injured reserve
Warner (ankle) was seen sprinting on the side during Thursday's practice, Matt Barrows of The Athletic reports.
Jan 07
Jan 04
Questionable
San Francisco head coach Kyle Shanahan relayed that Purdy suffered a "stinger" after taking a hard hit to his left shoulder on the 49ers' final offensive play of Saturday's 13-3 loss to the Seahawks, Noah Furtado and Eric Branch of the San Francisco Chronicle report. "It's just I got hit, and the left shoulder sort of lit up," Purdy said after the contest. "I feel good right now. We'll see how I feel [Sunday]."
Questionable
Winters could miss the wild-card round of the NFC playoffs due to an ankle injury he sustained during the 49ers' 13-3 loss to the Seahawks on Saturday, Noah Furtado and Eric Branch of the San Francisco Chronicle report.
Questionable
Head coach Kyle Shanahan told reporters after the 49ers' 13-3 loss to the Seahawks on Saturday that Bethune's groin injury could prevent him from playing in the wild-card round of the NFC playoffs, Noah Furtado and Eric Branch of the San Francisco Chronicle report.
Jan 03
Out
Out
Robinson (coach's decision) is inactive for Saturday night's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
Out
Out
Out
Pearsall (knee/ankle) is inactive for Saturday's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
Out
Out
Williams (hamstring) is inactive for Saturday night's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
Dec 20, 2025
Out
Rourke (knee) is ruled out for Monday's game against the Colts, Briana Jeannel of the team's official site reports.
Out
Green (neck) has been ruled out for Monday's contest against the Colts, Matt Maiocco of NBC Sports Bay Area reports.
Out
Pearsall (knee/ankle) has been ruled out for Monday's game against the Colts, Matt Maiocco of NBC Sports Bay Area reports.
Injured reserve
Gross-Matos (hamstring/knee) is officially listed as questionable for Monday's game against the Colts, Matt Maiocco of NBC Sports Bay Area reports.
Dec 15, 2025
Questionable
Elliott (knee) is expected to practice this week, Matt Barrows of The Athletic reports.
Questionable
Martin remains in the league's concussion protocol Monday, Matt Barrows of The Athletic reports.
Questionable
Pearsall hauled in six of seven targets for 96 yards in Sunday's 37-24 win over Tennessee.
Questionable
Okuayinonu (ankle) is expected to return to practice during Week 16 prep, Matt Barrows of The Athletic reports.
Questionable
Head coach Kyle Shanahan relayed Monday that he expects Bethune (ankle) to return to practice for Week 16 prep, Matt Barrows of The Athletic reports.
Injured reserve
Head coach Kyle Shanahan said Monday that Gross-Matos (hamstring) should return to practice ahead of the 49ers' Week 16 tilt against the Colts on Monday, Dec. 22, Matt Barrows of The Athletic reports.
Dec 13, 2025
Out
The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.
Questionable
Although he was added to the 49ers' injury report Saturday, McCaffrey (back) is expected to play against the Titans on Sunday, Adam Schefter of ESPN reports.
Dec 12, 2025
Out
Rourke (knee) is out for Sunday's game versus the Titans, Cam Inman of The San Jose Mercury News reports.
Out
Martin (concussion) is out for Sunday's game versus Tennessee, Cam Inman of The San Jose Mercury News reports.
Out
Okuayinonu (ankle) has been ruled out for Sunday's game against the Titans, Cam Inman of The San Jose Mercury News reports.
Out
Bethune (ankle) has been ruled out for Sunday's game against the Titans, Cam Inman of The San Jose Mercury News reports.
Injured reserve
Gross-Matos (hamstring) is out for Sunday's game versus Tennessee, Cam Inman of The San Jose Mercury News reports.
Dec 08, 2025
Dec 02, 2025
Out
San Francisco general manager John Lynch reiterated Tuesday that he's still "hopeful" Aiyuk (knee) will play at some point this season, though Lynch acknowledged that he wasn't sure how realistic the wideout's return might be, Cam Inman of The San Jose Mercury News reports.
Dec 01, 2025
Out
Head coach Kyle Shanahan told reporters Monday that Bartch will be placed on injured deserve after spraining his foot during the 49ers' 26-8 win over the Browns on Sunday, David Lombardi of SFStandard.com reports.
Out
Pineiro (hamstring) is expected to return to action following the 49ers' bye week in Week 14, Matt Barrows of The Athletic reports.
Questionable
Juszczyk is dealing with a rib fracture ahead of the 49ers' bye week, David Lombardi of SFStandard.com reports.
Out
Out
Bethune (ankle) is closing in on a return to action, Matt Barrows of The Athletic reports.
Nov 30, 2025
Questionable
Martin has exited Sunday's game against the Browns and is being evaluated for a possible concussion, Nick Wagoner of ESPN.com reports.
Nov 27, 2025
Questionable
Beal (concussion) logged a full practice Wednesday, Cam Inman of The San Jose Mercury News reports.
Nov 26, 2025
Out
Aiyuk (knee) won't return to practice this week, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Pineiro (hamstring) will not participate in practice Wednesday, Cam Inman of The San Jose Mercury News reports.
Questionable
Gifford (hip/neck) was a limited participant at practice Wednesday, Matt Barrows of The Athletic reports.
Out
Okuayinonu (ankle) is expected to miss multiple weeks, Matt Barrows of The Athletic reports.
Questionable
Bethune (ankle) was absent from practice Wednesday, Matt Barrows of The Athletic reports.
Injured reserve
Head coach Kyle Shanahan relayed Wednesday that the 49ers will not designate Gross-Matos (knee) to return from injured reserve, Matt Maiocco of NBC Sports Bay Area reports.
Nov 23, 2025
Out
The 49ers remain committed to getting Aiyuk (knee) "healthy and back on the field" in 2025, even though the team had approximately $27 million in guarantees for the 2026 season voided in his contract, Mike Garafolo of NFL Network reports.
Nov 22, 2025
Out
Pineiro (hamstring) has been ruled out for Monday's game against the Panthers, Cam Inman of The San Jose Mercury News reports.
Questionable
Gifford (hip/neck) is questionable for Monday night's game against the Panthers, Cam Inman of The San Jose Mercury News reports.
Doubtful
Beal (concussion) is listed as doubtful for Monday night's game against Carolina, Cam Inman of The San Jose Mercury News reports.
Out
Bethune (ankle) has been ruled out for Monday's game against Carolina, Cam Inman of The San Jose Mercury News reports.
Nov 17, 2025
Out
Coach Kyle Shanahan said Monday that Aiyuk's (knee) 21-day practice window will not be opened this week, and he remains week-to-week, Matt Barrows of The Athletic reports.
Questionable
Coach Kyle Shanahan said Monday that Pineiro (hamstring) is considered week-to-week, David Lombardi of SFStandard.com reports.
Injured reserve
Coach Kyle Shanahan said Monday that Cowing's (hamstring) 21-day practice window will likely be opened following the 49ers' Week 14 bye, Matt Maiocco of NBC Sports Bay Area reports.
Doubtful
San Francisco head coach Kyle Shanahan said that Bethune suffered a right high-ankle sprain in Sunday's 41-22 win over the Cardinals and is expected to miss multiple weeks, David Lombardi of SFStandard.com reports.
Nov 16, 2025
Out
Out
Questionable
Pineiro (hamstring) is questionable to return to Sunday's game against the Cardinals, Eric Branch of the San Francisco Chronicle reports.
Out
Out
James (coach's decision) is inactive for Sunday's game against the Cardinals, Briana Jeannel of the 49ers' official site reports.
Out
Watkins (coach's decision) is inactive for Sunday's game against the Cardinals, Briana Jeannel of the 49ers' official site reports.
Out
Questionable
Beal suffered a concussion in the first half of Sunday's contest against Arizona, Jennifer Lee Chan of NBC Sports Bay Area reports.
Questionable
Bethune (ankle) is questionable to return to Sunday's contest against the Cardinals, Jennifer Lee Chan of NBC Sports Bay Area reports.
Nov 12, 2025
Questionable
Collins (hip) was a limited practice participant Wednesday, Cam Inman of The San Jose Mercury News reports.
Questionable
Coach Kyle Shanahan said Purdy (toe) will be a limited but "aggressive" participant at Wednesday's practice with the intention to start Sunday's game at Arizona, Cam Inman of The San Jose Mercury News reports.
Questionable
Winters (knee) was a limited practice participant Wednesday, Cam Inman of The San Jose Mercury News reports.
Questionable
Pearsall (knee) is returning to practice Wednesday, David Lombardi of SFStandard.com reports.
Nov 11, 2025
Questionable
Nov 10, 2025
Out
Head coach Kyle Shanahan said Monday that the 49ers don't intend to open Aiyuk's (knee) practice window this week, Nick Wagoner of ESPN.com reports.
Questionable
Coach Kyle Shanahan said Monday that Purdy (toe) will continue to increase his activity level this week, Nick Wagoner of ESPN.com reports.
Questionable
Coach Kyle Shanahan said Monday that Pearsall (knee) has a chance to practice Wednesday, Matt Barrows of The Athletic reports.
Nov 09, 2025
Out
Collins (hip) is inactive for Sunday's game against the Rams, Briana Jeannel of the 49ers' official site reports.
Out
Purdy (toe) is listed as inactive Sunday versus the Rams, Briana Jeannel of the 49ers' official site reports.
Out
Out
Out
Out
Out
Nov 08, 2025
Nov 06, 2025
Questionable
Collins has a hip injury and did not participate in Thursday's practice, Matt Barrows of The Athletic reports.
Questionable
Purdy (toe) remained limited at Thursday's practice, Cam Inman of The San Jose Mercury News reports.
Questionable
Huff (hamstring) was a limited participant in practice for the second day in a row Thursday, Matt Barrows of The Athletic reports.
Questionable
Winters (knee) was a limited participant in Thursday's practice, Matt Barrows of The Athletic reports.
Questionable
Davis (ankle) was a limited participant in practice Thursday, Matt Barrows of The Athletic reports.
Questionable
White was a limited participant in practice Thursday due to a groin injury, Matt Barrows of The Athletic reports.
Questionable
Pearsall (knee) didn't practice Thursday, Cam Inman of The San Jose Mercury News reports.
Questionable
Bethune (thigh) was a limited participant in practice for the second day in a row Thursday, Matt Barrows of The Athletic reports.
Nov 05, 2025
Out
San Francisco head coach Kyle Shanahan said Wednesday that he's "pretty confident" Aiyuk (knee) will play at some point this season, David Lombardi of SFStandard.com reports.
Nov 04, 2025
Questionable
Nov 03, 2025
Out
San Francisco head coach Kyle Shanahan said that Aiyuk (knee) won't have his 21-day practice window opened this week, David Lombardi of SFStandard.com reports.
Out
Out
Out
Head coach Kyle Shanahan said Monday that Williams tore his ACL during the fourth quarter of Sunday's 34-24 win over the Giants, Matt Barrows and Dianna Russini of The Athletic report.
Out
Coach Kyle Shanahan noted Monday that Pearsall (knee) has a chance to play Sunday against the Rams but will be evaluated mid-week, Matt Barrows of The Athletic reports.
Nov 02, 2025
Out
Purdy (toe) is inactive for Sunday's game against the Giants, Briana Jeannel of the 49ers' official site reports.
Nov 01, 2025
Injured reserve
Bartch (ankle) has been ruled out ahead of Sunday's game against the Giants.
Questionable
Elliott (ankle) is expected to play in Sunday's game against the Giants, Eric Branch of the San Francisco Chronicle reports.
Oct 31, 2025
Questionable
Purdy (toe) won't start Sunday's game against the Giants but is listed as questionable to be available in a backup capacity, Matt Maiocco of NBC Sports Bay Area reports.
Out
Huff (hamstring) has been ruled out for Sunday's game against the Giants, Jennifer Lee Chan of NBC Sports Bay Area reports.
Questionable
Winters (knee) is listed as questionable for Sunday's game against the Giants, Jennifer Lee Chan of NBC Sports Bay Area reports.
Out
Brendel (hamstring) was ruled out ahead of Sunday's matchup against the Giants,Jennifer Lee Chan of NBC Sports Bay Area reports.
Out
Pearsall (knee) won't play Sunday against the Giants, Cam Inman of The San Jose Mercury News reports.
Oct 30, 2025
Questionable
Purdy (toe) was limited at Thursday's practice, Nick Wagoner of ESPN.com reports.
Questionable
Winters (knee) was a limited participant in Thursday's practice, Eric Branch of the San Francisco Chronicle reports.
Questionable
Pearsall (knee) didn't take part in Thursday's practice, Cam Inman of The San Jose Mercury News reports.
Questionable
Okuayinonu (ankle) was a limited participant in Thursday's practice, Eric Branch of the San Francisco Chronicle reports.
Oct 29, 2025
Injured reserve
Bartch (ankle) was a limited participant in San Francisco's practice Wednesday, David Lombardi of SFStandard.com reports.
Questionable
Purdy (toe) officially was limited at Wednesday's practice, Eric Branch of the San Francisco Chronicle reports.
Questionable
Huff (hamstring) did not participate at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Questionable
Winters (knee) did not participate at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Questionable
Brendel (hamstring) didn't participate in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Questionable
Elliott (ankle) was a limited participant in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Questionable
Pearsall (knee) isn't practicing Wednesday, Vic Tafur of The Athletic reports.
Questionable
Okuayinonu (ankle) did not participate at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Injured reserve
Burford (knee) was a full participant in San Francisco's practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Questionable
Stout (shoulder) was a limited participant at practice Wednesday, Eric Branch of the San Francisco Chronicle reports.
Oct 28, 2025
Questionable
Questionable
Questionable
Questionable
Oct 27, 2025
Questionable
Out
Coach Kyle Shanahan said Monday that the 49ers don't intend to designate Aiyuk (knee) to return from the reserve/PUP list Wednesday, Matt Barrows of The Athletic reports.
Questionable
Purdy (toe) has a chance to return to action Sunday at the Giants, Nick Wagoner of ESPN.com reports. "It's too early to say," coach Kyle Shanahan said Monday. "I don't think it's a long shot. We'll see how he's doing on Wednesday."
Questionable
Head coach Kyle Shanahan said Monday that Winters is considered day-to-day due to a knee injury he sustained during Sunday's 26-15 loss to the Texans, Jennifer Lee Chan of NBC Sports Bay Area reports.
Questionable
Coach Kyle Shanahan said Monday that Jones suffered a bruised knee during Sunday's 26-15 loss at Houston and is "day-to-day," David Lombardi of SFStandard.com reports.
Oct 26, 2025
Out
Out
Out
Questionable
Winters (knee) has been ruled out for the rest of Sunday's game against the Texans.
Out
Questionable
Elliott (ankle) has been ruled out for the rest of Sunday's game against the Texans, Matt Maiocco of NBC Sports Bay Area reports.
Out
Out
Questionable
Okuayinonu is questionable to return to Sunday's matchup against Houston due to an ankle injury, Nick Wagoner of ESPN.com reports.
Out
Oct 25, 2025
Injured reserve
Burford (knee) has been ruled out for Sunday's game against Houston.
Oct 24, 2025
Out
Coach Kyle Shanahan said Friday that the 49ers may designate Aiyuk (knee) to return from the reserve/PUP list next week, David Lombardi of SFStandard.com reports.
Out
Purdy (toe) has been ruled out for Sunday's game at Houston, Nick Wagoner of ESPN.com reports.
Out
Huff (hamstring) has been ruled out for Sunday's game against the Texans, Nick Wagoner of ESPN.com reports.
Questionable
Lenoir (quadriceps) is listed as questionable for Sunday's game against the Texans, Nick Wagoner of ESPN.com reports.
Out
Brendel (hamstring) is listed as out for Sunday's game at Houston, Nick Wagoner of ESPN.com reports.
Questionable
Gifford (hamstring) is listed as questionable for Sunday's game at Houston, Nick Wagoner of ESPN.com reports.
Out
Pearsall (knee) has been ruled out for Sunday's game at Houston, Nick Wagoner of ESPN.com reports.
Out
Gross-Matos (knee/hamstring) has been ruled out for Sunday's game against the Texans, Nick Wagoner of ESPN.com reports.
Oct 21, 2025
Questionable
Questionable
Questionable
Questionable
Oct 20, 2025
Doubtful
Huff is expected to miss a couple weeks due to a hamstring injury, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Head coach Kyle Shanahan said Monday that Brendel is expected to be sidelined for a couple of weeks due to a hamstring injury, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Head coach Kyle Shanahan relayed Monday that Green (toe) will be considered day-to-day heading into the 49ers' Week 8 clash against the Texans on Sunday, Nick Wagoner of ESPN.com reports.
Oct 19, 2025
Out
Out
Questionable
Brendel has a hamstring injury and has been ruled out for the rest of Sunday night's matchup with the Falcons, Matt Maiocco of NBC Sports Bay Area reports.
Out
James (coach's decision) is inactive for Sunday Night Football against the Falcons.
Out
Watkins (coach's decision) is inactive for Sunday night's matchup with the Falcons.
Questionable
Green (toe) has been ruled out for the rest of Sunday night's game against the Falcons, Nick Wagoner of ESPN.com reports.
Out
Out
Oct 18, 2025
Oct 17, 2025
Out
Purdy (toe) has been ruled out for Sunday's game against Atlanta, Matt Barrows of The Athletic reports.
Injured reserve
Head coach Kyle Shanahan said Friday that Cowing (hamstring) is "getting close" to returning from injured reserve, Nick Wagoner of ESPN.com reports.
Questionable
Green (neck) is listed as questionable for Sunday's game versus the Falcons, Nick Wagoner of ESPN.com reports.
Out
Pearsall (knee) has been ruled out for Sunday's game against the Falcons, Matt Barrows of The Athletic reports.
Questionable
Stout (shoulder) injured his ankle during Thursday's practice and is questionable to play against the Falcons on Sunday, Noah Furtado of the San Francisco Chronicle reports.
Out
Gross-Matos (knee/hamstring) is listed as out for Sunday's game versus Atlanta, Nick Wagoner of ESPN.com reports.
Oct 16, 2025
Questionable
Purdy (toe) was a limited practice participant Thursday, Cam Inman of The San Jose Mercury News reports.
Out
49ers coach Kyle Shanahan said Tuesday that Warner (ankle) has undergone successful surgery to address the right dislocated and fractured ankle he suffered Week 6, Matt Barrows of The Athletic reports.
Injured reserve
Kittle (hamstring) practiced in a limited capacity Thursday, Cam Inman of The San Jose Mercury News reports.
Questionable
Jennings (ankle/rib/shoulder) was a limited practice participant Thursday, Cam Inman of The San Jose Mercury News reports.
Questionable
Watkins (calf) was a limited participant in practice for the second day in a row Thursday, Cam Inman of The San Jose Mercury News reports.
Injured reserve
Givens (pectoral) was a full participant at practice Thursday, Cam Inman of The San Jose Mercury News reports.
Questionable
Valdes-Scantling missed Thursday's practice due to a calf injury, Cam Inman of The San Jose Mercury News reports.
Questionable
Pearsall (knee) was a non-participant at Thursday's practice, Cam Inman of The San Jose Mercury News reports.
Questionable
Moore (ankle) was a limited participant in practice Thursday after missing Wednesday's session, Cam Inman of The San Jose Mercury News reports.
Oct 15, 2025
Questionable
Questionable
Green (neck) was a limited participant at practice Wednesday, Cam Inman of The San Jose Mercury News reports.
Oct 14, 2025
Questionable
Questionable
Questionable
Questionable
Oct 13, 2025
Out
Coach Kyle Shanahan said Monday that Aiyuk (knee) is getting "closer and closer" to being able to practice, but the 49ers don't have a specific timeline for the wide receiver to do so, Nick Wagoner of ESPN.com reports.
Out
Out
Warner (ankle) will undergo season-ending surgery Tuesday, Nick Wagoner of ESPN.com reports.
Injured reserve
Coach Kyle Shanahan said Monday that the 49ers expect Kittle (hamstring) to practice this week, Nick Wagoner of ESPN.com reports.
Out
Out
Out
Oct 12, 2025
Out
Head coach Kyle Shanahan told reporters after Sunday's 30-19 loss to the Buccaneers that Warner will undergo season-ending surgery on his right ankle, Nick Wagoner of ESPN.com reports.
Questionable
Jennings said after Sunday's loss to the Bucs that he played with five broken ribs against Tampa Bay, David Lombardi of SFStandard.com reports.
Oct 10, 2025
Injured reserve
Givens (pectoral) is out for Sunday's game against Tampa Bay, Greg Auman of Fox Sports reports.
Oct 09, 2025
Questionable
Collins (knee) was a limited participant at practice Thursday, Vic Tafur of The Athletic reports.
Questionable
Purdy (toe) didn't practice Thursday but was seen doing some conditioning work while wearing cleats, Cam Inman of The San Jose Mercury News reports.
Questionable
Jennings (ankle/rib) practiced in a limited fashion Thursday, Vic Tafur of The Athletic reports.
Questionable
Watkins (calf) did not participate at practice Thursday, Vic Tafur of The Athletic reports.
Questionable
Jones (knee/oblique) officially was limited at Thursday's practice, Vic Tafur of The Athletic reports.
Questionable
Pearsall (knee) was working on the side with a sleeve on his right leg during Thursday's practice, Cam Inman of The San Jose Mercury News reports.
Oct 08, 2025
Questionable
Injured reserve
San Francisco head coach Kyle Shanahan said Wednesday that Kittle (hamstring) won't be available to play Sunday against the Buccaneers but could return from injured reserve for the 49ers' Week 7 game against the Falcons, David Lombardi of SFStandard.com reports.
Injured reserve
The 49ers designated Givens (pectoral) to return from injured reserve Wednesday.
Out
Mustapha (knee) practiced fully Wednesday, Eric Branch of the San Francisco Chronicle reports.
Questionable
Stout (ankle) was a limited practice participant Wednesday, Eric Branch of the San Francisco Chronicle reports.
Oct 07, 2025
Questionable
Questionable
Questionable
Questionable
Questionable
Oct 06, 2025
Out
The 49ers opened Mustapha's (knee) 21-day practice window to return from the reserve/PUP list.
Oct 03, 2025
Questionable
Collins sprained his knee during the 49ers' 26-23 overtime win over the Rams on Thursday, Nick Wagoner of ESPN.com reports.
Out
Head coach Kyle Shanahan confirmed after Thursday's 26-23 overtime victory over the Rams that Purdy is without a timeline for a return after a recent MRI revealed that he aggravated a turf toe injury in the Week 4 loss to the Jaguars, Ian Rapoport of NFL Network reports. "He's week-to-week," Shanahan said of Purdy. "Don't know how [the toe] will heal."
Injured reserve
San Francisco head coach Kyle Shanahan said Friday that Kittle (hamstring) is considered a "long shot" to be available for the team's Week 6 game against the Buccaneers, but the tight end could be more likely to return from injured reserve for a Week 7 matchup with the Falcons on Sunday, Oct. 19, Adam Schefter of ESPN reports.
Doubtful
Davis (hand) is set to undergo surgery after breaking his hand in Thursday's 26-23 win over the Rams, Ian Rapoport of NFL Network reports.
Out
Head coach Kyle Shanahan said Friday that the 49ers will aim to open Mustapha's (knee) 21-day practice window Monday, Matt Barrows of The Athletic reports.
Questionable
Head coach Kyle Shanahan relayed Friday that Stout is considered day-to-day due to an ankle sprain that he suffered during the 49ers' 26-23 overtime win over the Rams on Thursday, Nick Wagoner of ESPN.com reports.
Doubtful
Coach Kyle Shanahan said Friday that Gross-Matos will miss some time with a strained hamstring, Nick Wagoner of ESPN.com reports.
Oct 02, 2025
Injured reserve
Kittle has had no setbacks while on injured reserve due to a hamstring injury and has a chance to return Week 6 at Tampa Bay, Ian Rapoport of NFL Network reports.
Out
Out
James (coach's decision) is inactive for Thursday night's game against the Rams, Briana Jeannel of the 49ers' official site reports.
Out
Doubtful
Davis (hand) has been ruled out for the rest of Thursday night's game against the Rams, Ian Rapoport of NFL Network reports.
Out
Out
Out
Questionable
Gross-Matos has a hamstring injury and has been ruled out for the rest of Thursday's game against the Rams, Eric Branch of the San Francisco Chronicle reports.
Oct 01, 2025
Out
Purdy (toe) has been ruled out for Thursday's game at the Rams, Matt Maiocco of NBC Sports Bay Area reports.
Out
Jennings (ankle, ribs) is ruled out for Thursday's matchup against the Rams, Matt Maiocco of NBC Sports Bay Area reports.
Out
Watkins (calf) has been ruled out for Thursday night's game against the Rams, Matt Barrows of The Athletic reports.
Out
Pearsall (knee) is ruled out for Thursday's game against the Rams, Matt Maiocco of NBC Sports Bay Area reports.
Out
Beal (groin) has been ruled out for Thursday night's contest against the Rams, Matt Barrows of The Athletic reports.
Sep 30, 2025
Questionable
Purdy (toe) will be a non-participant in Tuesday's walk-through practice, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Questionable
Head coach Kyle Shanahan said that Jennings (ankle/ribs) won't participate in Tuesday's walk-through practice, Matt Maiocco of NBC Sports Bay Area reports.
Questionable
Questionable
Head coach Kyle Shanahan said that Pearsall (knee) won't participate in Tuesday's walk-through practice, Matt Maiocco of NBC Sports Bay Area reports.
Sep 29, 2025
Questionable
Winters was listed as a limited participant in Monday's estimated practice report due to a knee injury.
Out
Head coach Kyle Shanahan told reporters Monday that the 49ers are hopeful Mustapha (knee) can practice following the team's Week 6 matchup against the Buccaneers, David Lombardi of SFStandard.com reports.
Questionable
Questionable
Green (neck) was listed as a limited participant on Monday's estimated practice report.
Questionable
Questionable
Sep 26, 2025
Injured reserve
Bosa (knee) underwent surgery to address his torn ACL on Friday, Cam Inman of The San Jose Mercury News reports.
Sep 25, 2025
Out
49ers GM John Lynch said Thursday that Aiyuk (knee, PUP) is "not close" to returning, David Lombardi of SFStandard.com reports.
Sep 21, 2025
Sep 17, 2025
Injured reserve
Bartch (ankle) was placed on injured reserve Wednesday, Noah Furtado of the San Francisco Chronicle reports.
Sep 09, 2025
Aug 27, 2025
Injured reserve
The 49ers placed Cowing (hamstring) on injured reserve Wednesday.
Aug 26, 2025
Aug 19, 2025
Injured reserve
Taylor will undergo season-ending surgery to repair a fracture in his shoulder, Nick Wagoner of ESPN.com reports.
Jul 29, 2025
Injured reserve
Jackson (undisclosed) was discharged from the hospital and returned to the 49ers' training camp Monday, Matt Maiocco of NBC Sports Bay Area reports.
Jun 03, 2025
Injured reserve
The 49ers placed Taylor (undisclosed) on injured reserve Tuesday.
May 13, 2025
Injured reserve
Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log.