Week RS1 • 2025-09-07 • vs ATL (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bijan Robinson |
RB |
12 |
24 |
2.0 |
0 |
6 |
| 2 |
Tyler Allgeier |
RB |
10 |
24 |
2.4 |
0 |
5 |
Week RS2 • 2025-09-15 • vs HOU (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Woody Marks |
RB |
3 |
14 |
4.7 |
0 |
7 |
| 2 |
Nick Chubb |
RB |
12 |
43 |
3.6 |
1 |
25 |
Week RS3 • 2025-09-21 • vs NYJ (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Breece Hall |
RB |
9 |
21 |
2.3 |
0 |
17 |
Week RS4 • 2025-09-28 • vs PHI (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Saquon Barkley |
RB |
19 |
43 |
2.3 |
1 |
10 |
| 2 |
AJ Dillon |
RB |
3 |
17 |
5.7 |
0 |
11 |
Week RS5 • 2025-10-05 • vs SEA (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kenneth Walker III |
RB |
10 |
86 |
8.6 |
0 |
31 |
| 2 |
Zach Charbonnet |
RB |
9 |
36 |
4.0 |
1 |
8 |
Week RS6 • 2025-10-12 • vs SF (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Christian McCaffrey |
RB |
17 |
54 |
3.2 |
1 |
11 |
Week RS7 • 2025-10-20 • vs DET (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Jahmyr Gibbs |
RB |
17 |
136 |
8.0 |
2 |
78 |
| 2 |
David Montgomery |
RB |
13 |
21 |
1.6 |
0 |
6 |
Week RS8 • 2025-10-26 • vs NO (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Alvin Kamara |
RB |
6 |
21 |
3.5 |
0 |
5 |
Week RS10 • 2025-11-09 • vs NE (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
TreVeyon Henderson |
RB |
14 |
147 |
10.5 |
2 |
69 |
| 2 |
D'Ernest Johnson |
RB |
1 |
1 |
1.0 |
0 |
1 |
Week RS11 • 2025-11-16 • vs BUF (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
James Cook III |
RB |
16 |
48 |
3.0 |
0 |
8 |
| 2 |
Ty Johnson |
RB |
1 |
9 |
9.0 |
0 |
9 |
Week RS12 • 2025-11-23 • vs LAR (Away)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Kyren Williams |
RB |
12 |
46 |
3.8 |
0 |
9 |
| 2 |
Blake Corum |
RB |
7 |
24 |
3.4 |
0 |
10 |
Week RS13 • 2025-11-30 • vs ARI (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Michael Carter |
RB |
5 |
17 |
3.4 |
0 |
8 |
Week RS14 • 2025-12-07 • vs NO (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Devin Neal |
RB |
19 |
70 |
3.7 |
1 |
21 |
| 2 |
Evan Hull |
RB |
1 |
4 |
4.0 |
0 |
4 |
Week RS15 • 2025-12-11 • vs ATL (Home)
Season 2025
| Rank | Player | POS |
Att | Yds | Avg | TD | Long |
| 1 |
Bijan Robinson |
RB |
19 |
93 |
4.9 |
1 |
14 |
| 2 |
Tyler Allgeier |
RB |
2 |
18 |
9.0 |
0 |
15 |
